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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEFM All Species: 7.58
Human Site: Y115 Identified Species: 18.52
UniProt: P07197 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07197 NP_005373 916 102472 Y115 L N D R F A G Y I E K V H Y L
Chimpanzee Pan troglodytes Q5R1W8 466 53634
Rhesus Macaque Macaca mulatta XP_001106972 919 103102 Y115 L N D R F A G Y I E K V H Y L
Dog Lupus familis XP_543999 500 55446
Cat Felis silvestris
Mouse Mus musculus P08553 848 95898 Y119 G Y I E K V H Y L E Q Q N K E
Rat Rattus norvegicus P23565 505 56097
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508574 942 104269 F117 K G I R K I L F F Q D N F Q I
Chicken Gallus gallus P16053 858 95817 Y116 G Y I E K V H Y L E Q Q N K E
Frog Xenopus laevis P35617 470 53654
Zebra Danio Brachydanio rerio Q58EE9 444 51231
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.7 97 30.3 N.A. 83.7 30.8 N.A. 63.4 66.1 27.7 25 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 37.1 97.3 41.8 N.A. 86.7 42.5 N.A. 74 74.7 37.9 36 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 0 N.A. 13.3 0 N.A. 6.6 13.3 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 100 0 N.A. 33.3 0 N.A. 26.6 33.3 0 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 20 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 20 0 0 0 0 0 40 0 0 0 0 20 % E
% Phe: 0 0 0 0 20 0 0 10 10 0 0 0 10 0 0 % F
% Gly: 20 10 0 0 0 0 20 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 20 0 0 0 0 0 20 0 0 % H
% Ile: 0 0 30 0 0 10 0 0 20 0 0 0 0 0 10 % I
% Lys: 10 0 0 0 30 0 0 0 0 0 20 0 0 20 0 % K
% Leu: 20 0 0 0 0 0 10 0 20 0 0 0 0 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 20 0 0 0 0 0 0 0 0 0 10 20 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 20 20 0 10 0 % Q
% Arg: 0 0 0 30 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 20 0 0 0 0 0 20 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 20 0 0 0 0 0 40 0 0 0 0 0 20 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _